If you choose 3 student out of 100 students to go to Singapore, how many combination can you make?
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There are 100 students and you want to choose 3 of them. The problem is simply asking out of 100 chose 3, which is equivalent to:
( 3 1 0 0 ) = 3 ! ⋅ 9 7 ! 1 0 0 ! = 3 ! ⋅ 9 7 ! 1 0 0 ⋅ 9 9 ⋅ 9 8 ⋅ 9 7 ! = 3 ! ⋅ 9 7 ! 1 0 0 ⋅ 9 9 ⋅ 9 8 ⋅ 9 7 ! = 6 9 7 0 2 0 0 = 1 6 1 7 0 0