A Warning - Yellow Fever

A century ago, yellow fever was a source of terror—decimating populations and destroying economies. Mass vaccination campaigns led to a dramatic drop in cases worldwide; but the early 2000s witnessed a resurgence of the acute viral hemorrhagic disease in Africa and the Americas, where 40 countries are considered at highest risk.

Suppose a healthy mosquito of the genre Aedes or Haemogogus has a chance of P g P_g of getting infected upon bitting an infected person. If the chance of transmitting the virus upon a bite to a healthy person is P i P_i and the proportion of the infected human population is f f , what is the chance that a healthy mosquito will bite an infected person and just next infect a second (uninfected) person?


For more information about yellow fever, please visit CDC's page or WHO's page . If you live in a high-risk area, get vaccinated. We won't lose this fight.

P g P i ( f f 2 ) \frac{P_g}{P_i} \big(f - f^2\big) P g P i P_g P_i P g P i ( f f 2 ) P_g P_i \big(f - f^2\big) P g P i f 1 f 2 P_g P_i \frac{f}{1 - f^{2}}

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1 solution

The chance that a healthy mosquito is bitting someone who is infected is exactly the proportion of infected human population f f . We want the mosquito to get infected, so the probability of that happening is f P g f P_g . The probability that this mosquito is bitting someone who is not infected and infecting is ( 1 f ) P i (1 - f) P_i . Therefore the probability of a healthy mosquito bitting an infected person and just next infect (and therefore he was infected) a second (uninfected) person is just the product of these values:

P g P i f ( 1 f ) = P g P i ( f f 2 ) . P_g P_i f (1 - f) = P_g P_i (f - f^2).

Notice that this chance will look like this

where we can nicely see that the maximum probability of spreading the infection happens when exactly half of the population is sick ( f = 1 / 2 ) (f = 1/2) . We can also see that by maximizing the value of P ( f ) = P g P i ( f f 2 ) P(f) = P_g P_i (f - f^2) where P g P i P_g P_i is a constant:

P ( f ) = P g P i ( 1 2 f ) = 0 f = 1 / 2. P'(f) = P_g P_i (1 - 2f ) = 0 \;\; \Rightarrow f = 1/2.

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