Beware of the Cream Filling

Arteriosclerotic plaques forming on the inner walls of arteries can decrease the effective cross-sectional area of an artery. Changes in the effective area of an artery can lead to large changes in the blood pressure in the artery and possibly to the collapse of the blood vessel.

Consider an artery that is horizontal along some stretch. In the healthy portion of the artery the blood flow velocity is 0.14 m/s 0.14~\mbox{m/s} . If plaque closes off 80 % 80\% of the area of the artery at one point, what is the magnitude of the pressure drop in Pascals ?

Details and assumptions

  • The mass per unit volume of blood is ρ = 1050 kg/m 3 \rho= 1050~\mbox{kg/m}^3 .
  • You may neglect the viscosity of blood.


The answer is 246.96.

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10 solutions

Mursalin Habib
Jul 29, 2013

The velocity of blood in an artery is inversely proportional to the cross-sectional area of the artery.

In other words, A 1 v 1 = A 2 v 2 A_1 v_1=A_2 v_2 .

If plaque closes off 80 % 80\% of the area of the artery, the area is reduced to 1 5 \frac{1}{5} of the original area.

So, A 2 = A 1 5 A_2=\frac{A_1}{5} .

And our new velocity, v 2 v_2 is equal to 5 v 1 = 5 × 0.14 5v_1=5\times 0.14 m/s \text{m/s} = 0.7 =0.7 m/s \text{m/s} .

Now we are going to use something called Bernoulli's equation which tells us that the sum of the pressure, the gravitational potential energy per volume and the kinetic energy per volume of a fluid always remains the same [assuming we have no viscosity].

We can write the equation like this:

p 1 + ρ g h 1 + 1 2 ρ v 1 2 = p 2 + ρ g h 2 + 1 2 ρ v 2 2 p_1+\rho g h_1 + \frac{1}{2} \rho {v_1}^2=p_2+\rho g h_2 + \frac{1}{2} \rho {v_2}^2

where p p is the pressure, ρ \rho is the density, h h is the height and v v is the velocity of the fluid.

This equation can be rewritten like this:

p 1 p 2 = ρ g ( h 2 h 1 ) + 1 2 ρ ( v 2 2 v 1 2 ) p_1-p_2=\rho g (h_2-h_1) +\frac{1}{2}\rho ({v_2}^2- {v_1}^2) .

Notice that the artery is horizontal implying h 2 = h 1 h_2=h_1 .

So our equation can be further simplified into:

p 1 p 2 = 1 2 ρ ( v 2 2 v 1 2 ) p_1-p_2= \frac{1}{2}\rho ({v_2}^2- {v_1}^2) .

We know all the values of the terms in the right hand side of this equation.

So, plugging them in gives us the pressure drop, p 1 p 2 = 246.96 p_1-p_2= \boxed{246.96} Pascals \text{Pascals} .

Moderator note:

Nicely written. Good background on Bernoulli.

Varun Kaushik
Jul 28, 2013

new cross-sectional area = 0.14/5 = 0.028m/s^2 , using equation of continuity, new velocity = 0.7m/s, Now, use bernoulli's equation neglecting height difference(since the artery is horizontal) to get the answer.

Lucas Guimarães
Jul 28, 2013

According to continuity equation:

A i v i = A f v f A_i v_i = A_f v_f

And using Bernoulli principle (neglecting elevation difference):

v i 2 2 + P i ρ = v f 2 2 + P f ρ \frac{v_i^2}{2} + \frac{P_i}{\rho} =\frac{v_f^2}{2}+ \frac{P_f}{\rho}

Since Δ P = P f P i \Delta P = P_f-P_i we have that:

Δ P ρ = v f 2 v i 2 2 \frac{ \Delta P}{\rho} = \frac{v_f^2-v_i^2}{2}

Δ P = ρ 2 ( v f 2 v i 2 ) \Delta P = \frac{\rho}{2} (v_f^2-v_i^2)

Δ P = ρ 2 ( v i 2 A i 2 A f 2 v i 2 ) \Delta P = \frac{\rho}{2} (v_i^2\frac{A_i^2}{A_f^2} -v_i^2)

Δ P = ρ 2 v i 2 ( A i 2 A f 2 1 ) \Delta P = \frac{\rho}{2}v_i^2(\frac{A_i^2}{A_f^2}-1 )

Substituting ρ = 1050 k g / m 3 \rho = 1050\:kg/m^3 , A f = 0.2 A i A_f = 0.2 A_i and v i = 0.14 m / s v_i = 0.14\:m/s :

Δ P = 1050 2 0.1 4 2 24 \Delta P = \frac{1050 }{2}0.14^2 24

Δ P = 246.96 P a \Delta P = 246.96\: Pa

Raymond Lin
Aug 1, 2013

The flow rate must be constant, so we have A 1 v 1 = A 2 v 2 A_1v_1=A_2v_2 , or A 1 ( 0.14 ) = 0.2 A 1 v 2 A_1(0.14)=0.2A_1v_2 , getting that v 2 = 0.7 v_2=0.7 .

Next, we use Bernoulli's Equation, p 1 + ρ g y 1 + 1 2 ρ v 1 2 = p 2 + ρ g y 2 + 1 2 ρ v 2 2 p_1+\rho g y_1+\frac{1}{2} \rho v_1^2=p_2+\rho g y_2+\frac{1}{2} \rho v_2^2 . Since y 1 = y 2 y_1=y_2 , we have that p 1 + 1 2 ρ v 1 2 = p 2 + 1 2 ρ v 2 2 p_1+\frac{1}{2} \rho v_1^2=p_2+\frac{1}{2} \rho v_2^2 , or that p 2 p 1 = 1 2 ρ ( v 2 2 v 1 2 ) |p_2-p_1|=\frac{1}{2} \rho (|v_2^2-v_1^2|) . Plugging in our values, we get that the answer is 1 2 ( 1150 ) ( 0. 7 2 0.1 4 2 ) = 246.96 \frac{1}{2}(1150)(|0.7^2-0.14^2| )= \fbox{246.96}

Kevin Fei
Jul 29, 2013

First we wish to relate the speeds of blood in the two areas of the vessels. We use the continuity equation:

A 1 v 1 = A 2 v 2 A_{1}v_{1} = A_{2}v_{2}

A 1 ( 0.14 m / s ) = ( 1 0.8 ) A 1 v 2 A_{1} (0.14 m/s) = (1 - 0.8)A_{1}v_{2}

v 2 = 0.70 m / s v_{2} = 0.70 m/s

Now we use Bernoulli's Principle to find the pressure difference. We note that the artery is horizontal so the ρ g h \rho gh cancels giving us:

P 1 + 1 2 ρ v 1 2 = P 2 + 1 2 ρ v 2 2 P_{1} + \frac{1}{2} \rho v_{1}^{2} = P_{2} + \frac{1}{2} \rho v_{2}^{2}

P 1 P 2 = 1 2 ρ ( v 1 2 v 2 2 ) | P_{1} - P_{2} | = \frac{1}{2} \rho (v_{1}^{2} - v_{2}^{2})

= 1 2 ( 1000 k g / m 3 ) ( ( 0.7 m / s ) 2 ( 0.14 m / s ) 2 ) = \frac{1}{2} * (1000 kg/m^{3}) * ((0.7 m/s)^{2} - (0.14m/s)^{2})

= 246.96 P a = 246.96 Pa

Derp: ρ = 1050 k g / m 3 \rho = 1050 kg/m^{3}

Kevin Fei - 7 years, 10 months ago

From equation of continuity, a 1 v 1 = a 2 v 2 a_1 v_1 = a_2 v_2 , [ a a is area of CS] calculate v 2 v_2 .Use Bernoulli equation:

v 1 2 2 + P 1 ρ = v 2 2 2 + P 2 ρ \frac{v_1^2}{2} + \frac{P_1}{\rho} = \frac{v_2^2}{2} + \frac{P_2}{\rho}

Evaluate P 1 P 2 = ρ ( v 2 2 v 1 2 2 ) P_1 - P_2 = \rho(\frac{v_2^2 - v_1^2}{2}) . Substitute to get answer.

Doni Wardoyo
Jul 29, 2013

Let a normal artery has an area, A and Let the dirty artery has an area A' . We know that A x v (the blood velocity) is equal to A' x v'(the blood velocity in the other side of artery). A x v = A' x v' ==> where A' is only 20 % left. This can make us to know that 5 x v = v'. Then now we use the Bernoulli equations : 0.5 x ρ x v² + P(v) = 0.5 x ρ x v'². ==> substitute 5 x v = v' to this sequence and we get : 0.5 x ρ x (v'² - v²) = P(v). Substituting the number and we get P(v) = 0.5 x 1050 x (25 x v² - v²) ==> P(v) = 0.5 x 1050 x (24 x 0.14²) = 246.96 Pa.

Rajath Krishna R
Jul 28, 2013

Let the area at the healthy portion of the artery be A then, the area of the weak portion is A/5. By equation of continuity,

                                                A1v1=A2v2

                                          i.e A*0.41=A/5 *v2

                                               v2=0.7 m/s.

By Bernoulli's theorem,

                                     P1 + d*g*v1^2 = P2 + 1/2*d*v2^2                                                                   

                                               (d=density=1050 kgm^-3)


                       Pressure drop = P1-P2 = 1/2*d*( v2^2-v1^2)

Plug in the values and get the answer!!!!!!!!!!

Its 1/2 d v1^2 and not d g v1^2 in the Bernoulli theorem.Sorry for the mistake.

Rajath Krishna R - 7 years, 10 months ago
Muralidhar Kamidi
Jul 28, 2013

Using Bernoulli's equation:

P h e a l t h y P u n h e a l t h y = 1 2 ρ ( v u n h e a l t h y 2 v h e a l t h y 2 ) P_{healthy} - P_{unhealthy} = \frac {1}{2} \rho (v_{unhealthy}^2 - v_{healthy}^2)

But v u n h e a l t h y v_{unhealthy} is 5 times v h e a l t h y v_{healthy} because the cross section at the unhealthy part is 5 times smaller.

Thus Δ P = 12 ρ v h e a l t h y 2 \Delta P = 12 \rho v_{healthy}^2

Because the flow of the blood is constant, the velocity of blood flow where the area of the artery decrease five times is v 2 = 5 v 1 = 0.7 m / s v_2=5v_1=0.7m/s .

According to Bernoulli's equation, the magnitude of the pressure drop is: Δ P = 1 2 ρ ( v 2 2 v 1 2 ) = 246.96 P a \Delta P=\frac{1}{2} \rho (v^2_2-v^2_1)=246.96 Pa .

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