Breaking Bad

Chemistry Level 2

You recently turned 50 and you have just been diagnosed with terminal lung cancer. You decide to try and make as much money as possible before you die so that your family can live comfortably. You turn to synthesizing heroin as you heard there is a lot of money in the business and that methylamine would be too difficult to access to synthesize methamphetamine. Little did you know morphine is also a difficult reactant to get your hands on. The chemical structure of morphine is given in the attached photograph. What other chemical would you mix with morphine if you wanted to create heroin as a product?

Ethanoic acid Ethanol Methanol Methanoic acid

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3 solutions

Anish Puthuraya
May 17, 2014

This is a simple case of Fischer Esterification . When you mix an alcohol with a carboxylic acid, there is loss of water, to form an ester.

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In this case, I have marked the two alcoholic positions. When Ethanoic Acid ( C H 3 C O O H \displaystyle CH_3COOH ) is added to the Morphine, the following reaction takes place :

alt text alt text

Note: The above reaction occurs at both the alcoholic positions, thus giving us Heroine as the product.

The question was nice, yet simple. But the setting of the atmosphere was not at all good. :)

A Brilliant Member - 7 years ago

Ethanoic Acid..

SUBHADIP BERA - 7 years ago

well if i say the problem is poor options(no offence). We can clearly see that an alcohol is converted to ester so the reactants that are alcohol are eliminated and since additional 2 carbons are added, ethanoic acid is our answer

siddharth shah - 7 years ago

GOOD QUESTION

Ronnel Einstein - 7 years ago

nice answer

Himanshu Mishra - 7 years ago
Trevor B.
May 17, 2014

I promise \textbf{promise} that I knew this from prior knowledge.

I'm not the best at chemistry, so I'm not going to go into the exact details, but I can offer this explanation: in the picture for heroin, you see the addition in the bottom left and top left corners is CH 3 COOH , \text{CH}_3\text{COOH}, which is ethanoic acid.

I actually do know this from prior knowledge (don't ask where, but I do).

Trevor B. - 7 years ago

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Pi Han Goh - 7 years ago

It is known as esterification reaction where one mole of morphine reacts with 2 moles of acetic acid(ethanoic acid) to form one mole of heroin(chemically diacetyl morphine) with the elimination of 2 moles of water in the presence of strong proton acid such as sulphuric acid.

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Thank you for the exact details!

Trevor B. - 7 years ago

Breaking bad? :'D It's simple, OH becomes R-C=O when acid is added.

Vivek Vaibhav - 6 years, 11 months ago

it may be good to know that Diacetylmorphine, Acetomorphine, Dual Acetylated morphine, Morphine diacetate are the synonyms of HEROIN. and thus acetic acid (ethanoic acid) is the answer!
i know it: My biology project is on #Narcotics

Yes, I had to guess which acid was it since I didn't know acetic = ethanoic.

Saya Suka - 2 months, 2 weeks ago

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