Which number is next?
1 5 21 277 _ _ _ _
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The difference between the first and second values is 4; the difference between the second and third values is the square of 4 or 16. The difference between the third and fourth value is the square of 16 or 256. The difference between the fourth and fifth value is the square of 256 or 65536
1 (+4) 5 (+16) 21 (+256) 277 (+65536) 65813