On some antibacterial agent it is claimed: “In less than 24 hours, an 8-million bacterial colony can be formed from a single bacterium.”.
Supposing that's true, what is the maximum duplication time (in seconds) of any of the bacteria considered?
Assumptions:
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The model for the exponential growth of a bacterial colony is the famous (and most simple) differential equation:
d t d N = λ N
The general solution can be written as:
N ( t ) = N 0 e λ t ,
in our case N 0 = 1 because there is only 1 bacterium at t=0.
Given that there is a 1-hour lag phase, which means no bacterial duplication during that period, the effective exponential growth lasts 23 hours.
Therefore we know (hypothetically) that after 23 hours of duplication , there are 8-million bacteria. So for this statement to be true, all the bacteria considered must have a duplication time smaller than some T m a x .
we want T m a x in seconds so we need to convert 23 hours in seconds, that's 82800s.
And since λ = T l n 2
T m a x is given by: N ( 8 2 8 0 0 ) = e T m a x l n 2 × 8 2 8 0 0 = 8 0 0 0 0 0 0 .
Solving for T m a x actually yields 3610,7s but we can't round it up because a 3611s duplication time would result in a colony with less than 8 million bacteria.
So the maximum duplication time is T m a x = 3 6 1 0 s
Note: This could also be done by using N ( t ) = 2 n as a model, where n, the number of generation, is given by: n = T t