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Rearranging 3 x + 4 x + 1 2 x − 1 6 x − 9 x = 1 , we get 3 x + 4 x + 1 2 x = 1 6 x + 9 x + 1 , where each terms of both the LHS and RHS is > 0 . Therefore, we can apply AM-GM inequality.
When 3 x + 4 x + 1 2 x − 1 6 x − 9 x = 1 , ⟹ LHS = RHS, and LHS equals RHS only when they are minimum at x = 0 because for x < 0 RHS is decreasing faster than LHS and for x > 0 RHS is increasing faster then LHS.